产品货号：
Z12422
中文名称：
Caspase 1(p20)/CASP1抗体
英文名称：
Anti-Caspase 1(p20)/CASP1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Caspase 1(p20)/CASP1 Antibody |
| 指标别名 | CASP1;IL1BC;IL1BCE;Caspase-1;CASP-1;Interleukin-1 beta convertase;IL-1BC;Interleukin-1 beta-converting enzyme;ICE;IL-1 beta-converting enzyme;p45 [Cleaved into:Caspase-1 subunit p20;Caspase-1 subunit p10] |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ELISA |
| 基因名称 | CASP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Caspase 1(p20)/CASP1 recombinant protein (Position:N132-H404). |
| 实际分子量 | 47KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Caspase 1,apoptosis-related cysteine protease,is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta,IL18,and IL33 precursor proteins.Caspase 1 was purified ICE from the cytosol of the THP.human monocytic cell line and found that the active protease was made up of 2 peptides,which they called p20 and p10 based on their apparent molecular masses by SDS-PAGE.It belongs to a family of cysteine proteases known as caspases that always cleave proteins following an aspartic acid residue.The Caspase1 gene consists of 10 exons spanning at least 10.6kb.The Caspase 1 gene is mapped to 11q23,a site frequently involved in rearrangement in human cancers,including a number of leukemias and lymphomas,by Southern DNA blot analysis of rodent-human hybrids and by in situ hybridization to normal human metaphase chromosomes.Caspase 1 has been shown to induce cell necrosis or pyroptosis and may function in various developmental stages. |
| Uniprot ID | P29466 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | caspase 1 |
| 蛋白名全称 | Caspase-1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 ELISA 1:100～1000 |
| Gene ID | 834 |
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